PBI-4050 decreases adenine-induced tubulointerstitial injury and er-stress; implications of the GPR40 receptor

October 25, 2018
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PBI-4050 reduces systemic inflammation, electrolyte disturbances and renal injury in mice with sepsis-induced acute kidney injury
PBI-4050 reduces systemic inflammation, electrolyte disturbances and renal injury in mice with sepsis-induced acute kidney injury

PBI-4050 exerts anti-inflammatory and anti-fibrotic effects in several diabetic and non-diabetic models of ...

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PBI-4050 Improves Metabolic Regulation and Diabetic Nephropathy through Reduction of ER Stress, Pro-Inflammatory/Fibrotic Markers, Galectin-
PBI-4050 Improves Metabolic Regulation and Diabetic Nephropathy through Reduction of ER Stress, Pro-Inflammatory/Fibrotic Markers, Galectin-

These results suggest that PBI-4050 is a strong potential candidate for the treatment of metabolic diseases...